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dc.contributor.authorOdaibo, G. N.-
dc.contributor.authorOlaleye, O. D.-
dc.contributor.authorRuppach, H.-
dc.contributor.authorFasanmade, A. A.-
dc.contributor.authorOlubuyide, S. O.-
dc.contributor.authorDietrich, U.-
dc.identifier.otherBioscience Research Communications 13(4), pp. 459-464-
dc.description.abstractThe peptide binding immunoassay (PELISA) was used as previously described to determine HIV-I subtypes among 60 married HIV-I sero-positive individuals and their spouses identified at the University College Hospital, Ibadan in order to investigate the rate of heterosexual partners by different HIV-I subtypes in Nigeria. Out of the 60 couples whose blood samples were analyzed, 33 (55%) were both positive HIV while only one spouse of the couples was sero-positive among the other 27. Using the McNemer test for discordant paired samples, an insignificant (P=0.0636) differnce was obtained between male to female and female to male transmission. Subtypes A, B, C and E were dtected among these individuals. Most (82.3%) of the subtypes C and all of the subtype E(12) were detected among the tranmitters (couples with concordant sero-positive status). This study indicates that HIV-I subtypes C and E may be more efficiently transmitted heterosexually than the other subtypes.en_US
dc.publisherKlober Academic Publishersen_US
dc.subjectHIV-l sublypcs;en_US
dc.subjectHIV-1 predmee;en_US
dc.subjectConcordan[ coupla;en_US
dc.subjectDMmi mples;en_US
dc.titlePrevalence of HIV-I subtypes in infected concordant and discordant couples in Nigeraen_US
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